'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. 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I am having a lot of trouble making any sense of this study. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Metab.87 (2): 48999. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. For a better experience, please enable JavaScript in your browser before proceeding. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. I have posted the link, so you can see if it has any merit. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. Overtreatment, of course, is the hallmark danger of overdiagnosis. El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas. Privacy Policy. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to replacement therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. Brit Med J 1978, 1:210212. Hypothyroidism can cause depression and, without treatment, the symptoms intensify and directly affect the mental state. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. Symptoms. I posted it to see what anyone had to add. View the data on GreenMedInfos Hypothyroidism Research page. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer 1). Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. I do not believe in random events, of nature or otherwise. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Is so taking anti oxidants might be an idea. I have no further scientific evidence. Keep checking back for the register link to appear. Or, simply look at what the young-adult,T-score based definition of osteoporosis and osteopeniahas done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. I cried with joy when I found out there was something really wrong with me. Article published in Wakeup-World.Com. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. PMID: 23539727, [16] Alan R Gaby. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related diseases.. 2013 May ;98(5):1982-90. JavaScript is disabled. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. I have so much to say about this I could write a book. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". I wish I could say that my story was atypical. Unfortunately, it's quite typical. Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. I very much appreciate the information you shared. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. A place for patients and relatives. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a TSH suppressor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic self-fulfilling prophecy if you will. Increased sensitivity to cold. Nah, I would give this much credence. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. Tokushima J Exp Med 1991, 38:2535. Just another excuse for keeping us on doses that are too low. I think part of sharing information here on Inspire is the discussions about the articles we share. Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? In the U.S., the overall five-year survival rate for patients diagnosed with lung cancer is 25%, which is a 21% improvement over the . Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. PLoSone 2011, 11:e27547. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. In fact, it is the high levels of T4 that make them more susceptible to cancer. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. The Remarkable Heart-Friendy Properties of Avocados. However, I'm learning from science writer friends, researchers, and medical professionals that (1) some studies are better designed and carried out than others, and (2) some journalists are more careful about drawing conclusions and writing sensational headlines than others. Non-ASPS articles which could be relevant. Asesora y Consultora Web3 para empresas. Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Brit Med J 1978, 1:210212. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. Or that it was the many years of not being diagnosed with hypothyroidism, courtesy of daft blood test ranges, before finally tipping a TSH over 5 (or even 10) before treatment is commenced, by which time the damage is done. New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. ", That study is like a fishing expedition. Endocrinology 2008, 149:22412250. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. bear in the big blue house characters; colne times obituaries this week Menu Toggle. Angiology 2000, 51:S65S68. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. Endocrinol. In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. Article published in Wakeup-World.Com. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). If people do not wish to find out all they can about their disease that is fine too. As I am the caregiver for my dad who has Stage IV lung Cancer, I hope more research can be done on this topic soon. Now, I will bring it to the attention of my Endocrinologist. Acta Endocrinol 1988, 118:460464. If I can help someone, fine. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. That's all. Thank you for posting it, I agree we all need as much knowledge as we can get! Clin Cancer Res 2011, 30:77. I had doctor after doctor tell me it was in my head or I was menopausal. Tokushima J Exp Med 1991, 38:2535. Is This the Real Reason You're Exhausted All the T Why An Alkaline Approach Can Successfully Treat Ca We're Losing the War on Cancer- Here's Why. Scan this QR code to download the app now. Thanks, I am not suggesting I believe in all that I see. It may not display this or other websites correctly. To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Cookie Notice [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. She wrote about a product called Thyrtophin PMG. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. PLoSone 2011, 11:e27547. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a 'TSH suppressor.' Another recently approved drug is tepotinib (Tepmetko). I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? For more information, please see our I am just as much in the dark as some others on this site. I'm just saying the evidence presented in this article isn't very strong, and more study is needed to show Synthroid causes lung cancer. by D.ap Tue Feb 21, 2017 10:40 am, Powered by phpBB Forum Software phpBB Limited. [14] K A Woeber. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Just go on one of the thyroid sites and read the stories. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. Not what people like me are saying. International Journal of Human Nutrition and Functional Medicine, Black Seed May Treat Hypothyroidism (Hashimotos Disease), Clinical Trial Reveals, Wi-Fi Devices Increase Mercury Release From Dental Amalgams, Participating in Drum Circles Improves Health and Quality of Life in Parkinsons Patients (Study), Acupuncture Beats Injected Morphine for Pain: Groundbreaking Study, Mammography Is Harmful and Should Be Abandoned, Scientific Review Concludes, Killer Germs Obliterated by Medicinal Smoke Smudging, Study Reveals, Turmerics Smart Kill Properties Put Chemo & Radiation To Shame, Beet Juice Boosts Cognitive Function In One Dose, 13 Evidence-Based Medicinal Properties of Coconut Oil, Group Drumming Better Than Prozac, Study Suggests, 25 Cancer Stem-Cell Killing Foods That Are Smarter Than Chemo and Radiation, Ibuprofen Can Stop Your Heart 31% Increase in Cardiac Arrest Risk, Conscious Shopping Offering Conscious Products for Conscious People, Uncovering The Truths And Myths About 3 Superstar Herbs, Living Past 100: The Okinawan Diet and Blue Zone Centenarians, Repairs DNA and Rejuvenates Your Cells While You Relax, Why Daily Greens are the Real Fountain of Youth, T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. Untreated hypothyroidism increases morbidity and mortality. (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. Dr Childs guesses that patients on levothyroxine monotherapy may be more prone to cancer because they might be under-treated. This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Also, what is oxidised stress??? But that's just me. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Endocrinology 2008, 149:22412250. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Here members can share stories, find important information and learn from the experiences of others like themselves. They only reappear when I need to fine tune the medication. Gestionar el consentimiento de las cookies. Obesity epidemic caused by EMF exposures in the ho War on Health - The FDA's Cult of Tyranny. Endocrinology 1985, 117:12011208. J Clin Endocrinol Metab. With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Acta Endocrinol 1988, 118:460464. You must log in or register to reply here. I can understand why tennis 123 wrote, "I have so much to say about this I could write a book". 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. hyperthyroidism. Yes, lung cancer patients can have these symptoms, but so do patients who have other cancers. For more, visitGreenMedInfo.comand Facebook.com/GreenMedInfo, or sign up forGreenMedInfos free e-Newsletter. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. Post Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III).
Proviso West Basketball Alumni, Articles M
Proviso West Basketball Alumni, Articles M